منابع مشابه
Maximum recommended doses of local anesthetics: a multifactorial concept.
The current recommendations regarding maximum doses of local anesthetics presented in textbooks, or by the responsible pharmaceutical companies, are not evidence based (ie, determined by randomized and controlled studies). Rather, decisions on recommending certain maximum local anesthetic doses have been made in part by extrapolations from animal experiments, clinical experiences from the use o...
متن کاملA comparison of local anaesthetics for venepuncture.
AIM To compare the effectiveness of EMLA cream and Ametop gel in providing analgesia for venous cannulation. METHODS Single blind study in 120 children. RESULTS Both anaesthetic agents produced adequate analgesia. However, Ametop gel was more effective, with a statistically significant difference in the pain scores of the two groups (p < 0.05).
متن کاملQuinidine like activity of eight local anaesthetics.
and Md., Eight synthetic local anaesthetics from among (he Propiophenones, Benzil and Phenoxy derivatives and derivatives of Benzyl alcohol wen' examined for their arrhvthmia combating activity. Against acetylcholine induced auricular fibrillation U·0045 showed maximum activity and U -0172, U·OI77, U-OS75 and Lignocaine were more active than quinidine. In aconitine induced fibrillation li.OI77,...
متن کاملPeriodic Classification of Local Anaesthetics (Procaine Analogues)
Algorithms for classification are proposed based on criteria (information entropy and its production). The feasibility of replacing a given anaesthetic by similar ones in the composition of a complex drug is studied. Some local anaesthetics currently in use are classified using characteristic chemical properties of different portions of their molecules. Many classification algorithms are based ...
متن کاملNew Formulations of Local Anaesthetics—Part I
Part 1 comments on the types of local anaesthetics (LAs); it provides a better understanding of the mechanisms of action of LAs, and their pharmacokinetics and toxicity. It reviews the newer LAs such as levobupivacaine, ropivacaine, and articaine, and examines the newer structurally different LAs. The addition of adjuvants such as adrenaline, bicarbonate, clonidine, and corticosteroids is explo...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1995
ISSN: 0007-0912
DOI: 10.1093/bja/75.4.502